With due regard to the advantages of biological methods in significantly reducing waste and production costs, today these methods have replaced many chemical production methods. Currently, numerous units in the country are active in the field of industrial biotechnology, and efforts are underway to establish new units. In this context, the Industrial Biotechnology Research Group, spearheaded by a number of faculty members from the Chemical Engineering Department of Isfahan University of Technology, was established in 2001 (1390). The group’s research activities cover the biological production of various industrial materials, including biogas, biohydrogen, super-absorbents, ethanol, styrene, butanol, glutamic acid, a precursor for renewable polymer compounds, and also the production of food industry products such as yeast (fermentation starter), vinegar, glucose and fructose syrups, and enzymes such as glucoamylase and alpha-amylase. Other activities include solving problems and optimizing existing biological units, feasibility studies for biologically produced other industrial compounds, evaluation of different technologies for producing biological materials, and providing consulting services to investors, aiding in technology transfer, offering solutions to address wastewater treatment issues, and designing and establishing pilot semi-industrial plants.